David Mangelsdorf, a highly esteemed professor and renowned scientist at UT Southwestern Medical Center in Dallas, TX, has sadly passed away, leaving behind a lasting legacy in the field of biomedical science and the hearts of those who knew him. News of his death has sent waves of sorrow through the academic and scientific communities, both locally and around the world. Known for his groundbreaking research and his leadership in molecular biology and pharmacology, Dr. Mangelsdorf’s passing marks the end of a remarkable life dedicated to the pursuit of scientific knowledge and the education of future generations.
Dr. David Mangelsdorf was best known for his pioneering work in the field of nuclear receptor biology, particularly his collaborative discovery of orphan nuclear receptors and their roles in metabolism and disease. As Chair of the Department of Pharmacology at UT Southwestern, he led with vision, integrity, and passion, shaping the department into one of the top programs in the country. His research helped to unlock important mechanisms related to cholesterol metabolism, diabetes, and obesity, impacting the development of new treatments and improving the lives of countless patients.
Colleagues remember Dr. Mangelsdorf not only for his scientific brilliance but also for his mentorship and generosity. He was deeply respected by his peers, students, and collaborators for his humility, kindness, and unwavering dedication to advancing science for the benefit of humanity. His passing is a significant loss to UT Southwestern and the broader biomedical research community.
In addition to his scientific contributions, Dr. Mangelsdorf was a beloved member of the Dallas community. His influence extended beyond the lab, touching the lives of many through his work, compassion, and service. His commitment to excellence and innovation has inspired a generation of scientists who will carry forward his legacy.
David Mangelsdorf is survived by his family, friends, colleagues, and the many students he mentored throughout his career. His contributions will live on through the countless lives he impacted and the scientific discoveries he helped make possible.
A memorial service will be planned by UT Southwestern Medical Center to honor his memory and celebrate his life’s work. The community joins together in mourning this tremendous loss and offering condolences to those closest to him. Rest in peace, Dr. David Mangelsdorf.
